Becoming a living donor is a chance to save a life.

“Giving while living” can help recipients avoid long, uncertain waits for a kidney transplant1.

DID YOU KNOW?

It’s possible to live a full, healthy life with only one kidney.

What is Living Kidney Donation?

A living donor kidney transplant is the process of surgically removing a kidney from a healthy individual and placing it into a recipient who is in end stage renal disease (ESRD) and in need of a transplant. Living donors can choose to donate a kidney to a family member, friend, or altruistically to someone they don’t even know. Living donation may may help transplant recipients get off dialysis or avoid it if they’ve not yet started.

Receiving a kidney transplant from a living donor is an alternative to receiving one from a deceased donor.

Why Choose Living Donation?

Transplant is often referred to as a “Gift of Life”. A kidney transplant, either from a deceased donor or a living donor, allows the recipient to have as close to a normal life as possible. The generous donation of a living kidney donor transplant can provide the recipient with:

  • A longer life. Patients with a functioning transplanted kidney tend to live longer than those who remain on dialysis.
  • Better quality of life. Recipients may no longer need dialysis or, in some cases, may avoid dialysis altogether if they’ve not yet started (pre-emptive transplant).
  • Flexibility. Living kidney donation offers the ability to plan surgery at a time that works for everyone once the donor is approved for donation.
  • Improved outcomes. Organs from a living donor tend to function more quickly and last longer than those from deceased donors.
  • Increases transplant availability for others. Organs from a living donor free up a kidney for someone on the national transplant wait list who does not have a potential living donor, which reduces the shortage of organs.
  • Lower risks. Living kidney donation carries lower risks for complications or organ rejection than deceased kidney donation.
  • Shorter waiting time. The wait for a deceased donor kidney transplant can be three to seven years. With a living kidney, donor waiting times can be much shorter.

Who Can Be a Living Donor?

You don’t have to be a relative to become a living donor. In fact, you can be a parent, spouse, friend, acquaintance, or a total stranger (altruistic donor ) to the recipient. To be a living donor candidate, you must:

  • Be able and willing to comply with the follow-up care required after donation
  • Be free from active infections
  • Be free from diabetes
  • Be free from other organ damage
  • Be free from significant heart and/or lung disease
  • Be free from uncontrolled hypertension (cannot be on more than one blood pressure medication)
  • Be free from untreated or recent cancer diagnosis
  • Be in good health (physically and mentally)
  • Be over the age of 21 (in certain circumstances 18–20-year-olds can be considered)
  • Learn the risks and benefits of becoming a living donor
  • Provide consent after deciding if living donation is right for you

Are There Any Benefits to the Kidney Donor?

While there is no health or financial benefit to the living kidney donor, most donors express a psychological benefit of donating a kidney.

They have personal satisfaction knowing they were able to help a loved one, friend, or even a stranger. By donating, a living donor has also helped everyone who doesn’t have a living donor as there is now one less person waiting on the list for a kidney transplant.

While rare, it’s also possible that previously unknown medical problems are identified during living donor labs and workups, which can then be treated earlier by your primary care team.

What Happens to the Living Donor’s Kidney Health After Transplant?

After donating a kidney, between 25-35 percent of kidney function may be lost— however, the remaining kidney will pick up some of the work of the donated kidney and is able to provide what the donor needs to survive2.

There is risk of complication with any major surgery, but most healthy individuals who choose to donate a kidney have the same life expectancy, general health, and kidney function as non-donors.

RIGHT TO WITHDRAW

All those considering living kidney donation have the right to withdraw participation in the donation process at any time, during any stage of the process. You should not feel pressured or obligated to undergo the procedure. If you wish, the donor team can inform the recipient that you are no longer a donor candidate.

None of your health information will be shared with the potential recipient. At all stages, you may discuss any of your concerns with members of the Living Donor Team and Independent Living Donor Advocates (ILDA)

More On the Living Donor Kidney Transplant Process
Ever wonder what the process of becoming a living donor is like? From compatibility testing and referrals to transplant day and beyond, learn the process below.
Donor and Recipient Compatibility
Care teams will draw blood work to determine donor compatibility with the potential recipient.

ABO blood typing is a test used to determine your blood type.

  • Blood type A can donate to an A or AB recipient.
  • Blood type AB can donate to an AB recipient.
  • Blood type B can donate to a B or AB recipient.
  • Blood type O is a universal donor and can donate to a blood type A, B, AB or O recipient .

Tissue Typing (HLA) is a blood test that determines how closely donor tissues match those of the recipient. The purpose of a human lymphocyte antigen (HLA) blood test is to identify tissue type and to make sure that you and the intended recipient are a compatible genetic match.

What if I’m not a good match for my intended recipient?
If blood work shows that the donor kidney is not a good match, paired kidney donation (PKD) is another potential option for living kidney donation. In the PKD program, donors who do not match their intended transplant recipient may choose to take part in a paired donation program. The program can arrange a “swap,” which involves a pair of two living donors and two recipients. If the recipient from the first pair is compatible with the donor from the other pair—and vice versa— the transplant program may arrange the “swap” to allow two transplant recipients to receive living donor kidneys and allow two donors the ability to donate3.

Learn more about programs for incompatible donor/recipient pairs.

The Referral Process

Those considering becoming a living donor must start the evaluation process to become a living donor by calling WVU Medicine Transplant Alliance at 304-974-3004. (Friends and family members may not call for you.) Those interested may also complete the History and Health Questionnaire.

WVU Medicine respects the privacy of all potential donors and intended recipients. Once your referral is received, you will be assigned to a Living Donor Coordinator. This individual will be a separate coordinator from the intended recipient’s transplant team in order to prevent sharing of medical information.

Complete the Health History Questionnaire

Potential living kidney donors will receive educational materials and a Health History Questionnaire (HHQ) to be completed.

Once we receive your completed HHQ, a team will review your records. If you move forward as a potential candidate, you’ll be scheduled a call with the Independent Living Donor Advocate (ILDA) and attend a phone educational session with the Living Donor Coordinator.

What is an ILDA?

An Independent Living Donor Advocate (ILDA) is independent of the transplant department and has a background in ethics, transplantation, living donation, and informed consent. Involved throughout the entire transplant experience, the ILDA is responsible for:

  • Protecting and promoting the interests of the donor
  • Representing and advise the donor
  • Respecting the donor’s decision and ensuring the donor’s decision is informed and free from coercion
Educational Session

During the educational session, our team members will discuss the Living Donor Evaluation Consent and obtain your verbal consent to move forward. You will receive prescriptions for a 24-hour urine collection and initial blood work via the mail, and a 24-hour blood pressure monitor will be ordered for you.

You may complete all testing at your convenience and near your home. When the results come back, the Living Donor Team will review them and determine if an on-site evaluation can be scheduled.

A coordinator will contact you about your results and plans from there. Your results will also be available in the WVU Medicine MyWVUChart App.

On-Site Evaluation and Testing

If you are invited for an on-site evaluation, you’ll arrive at the WVU Medicine J.W. Ruby Memorial hospital in Morgantown, West Virginia for an all-day appointment. (You’ll receive details on the timing of this appointment, which may vary for each patient.)

Your day will include a visit to the WVU Medicine Transplant Alliance clinic where you will meet all team members and the Independent Living Donor Advocate (ILDA).

During this visit, you’ll have the following tests done:

  • Additional lab work drawn (These labs are not fasting so eat and drink as normal.)
  • Additional testing may be ordered based upon age, medical history, and/or family history
  • CT scan of your kidneys and abdomen (The CT scan requires contrast to enhance the images we need to assess the anatomy of your kidneys.)
  • Echocardiogram (ECHO) of your heart

During the on-site evaluation, labs will be drawn to determine compatibility.

  • Crossmatch/HLA Typing – This test will determine how closely blood/tissues match those of the recipient.

Following the in-person visit with the Living Donor Team, you will be scheduled for a MyWVUChart Virtual Visit with Behavioral Health assessment.

Living Donor Selection Committee (LDSC)
Once all testing is complete, the Living Donor Selection Committee (includes Living Donor Team, ILDAs, Behavioral Health Team, and Recipient Coordinator) will meet to review all testing to ensure each patient considering donation is physically and mentally capable of moving forward as a living donor.

You will be notified of the outcome of this meeting (accept, defer, or decline) by the Living Donor Coordinator.

  • Accepted: Approved for donation
  • Declined: Not a candidate for donation
  • Deferred: Sometimes additional testing is necessary for the team to make a final decision.
Pre-op to Discharge

Scheduling Living Donation Surgery

Once approved, the Living Donor Coordinator will call you to discuss timing, which will be determined by schedules/preferences of both the donor and recipient. Once a date for surgery is set, a pre-operative visit (within 14-30 days prior to the donation) will be scheduled.

Pre-op Visit

You’ll visit the WVU Medicine Transplant Alliance for your pre-op visit. During this visit:

  • The ILDA will meet with you.
  • The Living Donor Coordinator will provide instruction for pre-op meals, medications, and arrival times.
  • The surgeon will complete a history and physical (H&P) to be used for the surgery.
  • You will sign a consent for the operating room for a Living Donor Nephrectomy.

Additionally, you’ll visit the Anesthesia team at the Physician’s Office Complex (POC). Here you’ll receive blood work, an EKG, and a chest Xray. Our team will also utilize labs to perform the final Crossmatch testing to assess possible reactions between donor and recipient.

Surgery Day

Both the donor and recipient will arrive at WVU Medicine J.W. Ruby Memorial in the morning as communicated by the team. You (in addition to a maximum of two family members) will head to the fifth-floor pre-op area where you’ll change into a gown, receive an IV, and begin required blood work.

Your support team can come back at this time. Finally, the Donor Surgeon will see you in the holding area to mark your abdomen on the side the kidney is to be removed, and members of the Anesthesia and Operating Rooms teams will also stop by.

In the Operating Room

In the operating room, your surgical team will ask your name and who you are donating to.

Your surgery should take around three to four hours.

Your care team will insert a Foley Catheter to drain your bladder and work to position you on your side for the surgery. They will use foam and towels used to help protect boney areas and prevent pressure on nerves.

Your surgeon will make an incision around your belly button. After the kidney is removed, your surgeon will carefully close the incision with stitches.

Post Donation

Following surgery, you will rest in the Post-Anesthesia Recovery Room for at least 90 minutes.

Your care team will wake you up and manage any pain you might have. Then, you’ll head to the Step-Down Unit where your family can visit with you.

Discharge is planned for two days after donation.

 

Recovery
Every person recovers at their own rate.

The hospital staff will encourage you to get up and/or walk regularly to get your bowels moving and help the air/gas placed in your abdomen during surgery to resolve.

For a few weeks after surgery, you might feel more tired than normal. Keep up a light exercise program, especially walking, to build your energy back up.

Become a Living Donor Through the WVU Medicine Transplant Alliance Living Donor Program

If you are interested in becoming a living kidney donor, please call WVU Medicine Transplant Alliance at 304-974-3004 and relay your interest. A packet will be mailed to you with educational materials and a Health History Questionnaire to review, complete, and return. Once returned, a Living Donor Coordinator will reach out to you with next steps.
Learn more about becoming a living donor via the following resources: