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Vincent Setola, PhD Assistant Professor – Director, Laboratory of Neuroscience and Genetics of Addiction



Physiology, Pharmacology, & Neuroscience; Behavioral Medicine & Psychiatry; Blanchette Rockefeller Neurosciences Institute

Graduate Training

Université Pierre et Marie Curie (Paris VI) (MSc); Case Western Reserve University School of Medicine (PhD)


Université Pierre et Marie Curie (Paris VI); plasmalemmal monoamine transporter-G protein-coupled receptor interactions

Research Interests

Our group is currently interested in the genetics of opioid addiction and treatment outcome. We are working with colleagues at the Chestnut Ridge Comprehensive Opioid Addiction Treatment (COAT) clinic to recruit volunteers into a genetic study of polymorphisms that predict success in the COAT paradigm. We are also working with collaborators at Marshall University to identify, via whole-exome sequencing of mother-baby dyads, susceptibility loci for neonatal abstinence syndrome. Finally, our lab has a mouse model of altered response to drugs of addiction, which we are using to better understand the brain regions and molecular players involved in the signal transduction pathways of drugs of abuse.

Research Topics
  1. Drug abuse
  2. G protein signaling
  3. Human genetics
  4. Monoamine transporters
  5. Signal transduction
  6. Single nucleotide polymorphisms

Lab Personnel + Collaborators

James Berry
Cassie Brode
Stephan Brooks
Jim Denvir (MU)
Nick Dunbar
Richard Egleton (MU)
Bruno Giros (McGill Univ., UPMC, Paris VI)
Joshua Gross
Marc Haut
Niel Infante
Shane Kaski
Terry Kenakin (UNC)
Laura Lander
Luc Maroteaux (UPMC, Paris VI)
Marie-Christine Miquel-Vilette (Univ. de Toulouse)
Cathy O’Dell
Ryan Percifield
Don Primerano (MU)
Adam Schroer
David Siderovski
M. Cody Smith
C. Rolly Sullivan
Kimberley Wix

Recent Publications

Dr. Setola’s recent publications

WVU Rockefeller Neuroscience Institute