Addiction
Addiction happens when drugs “hijack” the brains reward center, making drugs and drug-seeking the primary focus. In particular, opioid use disorder is a problem in West Virginia and across the US. In order to reduce this misappropriation of the reward functioning of the brain, the RNI is investigating three ways of modulating the activity of that function.
Transcranial magnetic stimulation for the treatment of addiction
In collaboration with Magstim, we are using transcranial magnetic stimulation to improve the outcomes of those who have failed standard treatment for addiction.
Focused ultrasound for the treatment of addiction
Low-intensity Focused Ultrasound (LiFU) is being tested in collaboration with Insightec as a method to change the functioning of the reward centers of the brain in patients with opioid use disorder.
Deep brain stimulation for Opioid Use Disorder
Funded by the National Institute of Drug Abuse (NIDA) and in collaboration with company partner Medtronic, we are testing the use of deep brain stimulation (DBS) for individuals who have treatment-refractory opioid use disorder and have a high risk of death from overdose or other related causes. These patients have multiple attempts at treatment programs without long-term success in staying sober.
If you are interested in learning more about the RNI’s addiction research studies, please call 304-293-3460 or email rniresearch@hsc.wvu.edu.